Atomic Insights into Complex Materials – High-end Atom Probe Tomography and the Story behind it
One could wonder what is the next step in all this? What are the next frontiers? To me, it is deploying the strength of atom probe to the analysis of liquids, liquid-solid interfaces and soft matter. Since the 1950s, several scattered investigations of biological materials by atom probe have been reported, but without a sustained effort that would have enabled true breakthroughs. In parallel, the development of cryo-TEM has initiated a revolution in the biological sciences, enabling to image proteins and viruses at an unprecedented resolution. Atom probe could, here again, provide precious and unique insights – an example is the presence of metallic species suspected to be involved in the Alzheimer disease. A few years ago, we started looking at such proteins in a collaboration with a group at Heinrich Heine University Düsseldorf. The grant from the Leibniz Prize will allow to complete this research, via cryo-specimen preparation, transport and analysis of frozen liquids, which can be used as carriers of such biological materials.
I really want to thank Prof. Dierk Raabe for opening the door for me to come back to research after spending some years at Elsevier, and do what I do best.
Un grand Dankeschön.
I want to say how grateful I am for the support I get from Sandy, my wife, who’s been putting up with me for 20 years and with whom we have lived in 5 countries, and our lovely daughter Violette. To quote a great Canadian poet: "everything I do, I do it for you".