Reimar Lüst Lecture 2017 „High-throughput with particle technology for toxicology and materials discovery“
- Datum: 29.11.2017
- Uhrzeit: 17:00 - 18:30
- Vortragende(r): Prof. Dr. Lutz Mädler
- Ort: Max-Planck-Institut für Eisenforschung GmbH
- Raum: Seminar Room 1
- Gastgeber: Max-Planck-Institut für Eisenforschung GmbH
- Kontakt: rco@mpie.de
Abstract:
High-throughput screening is a well-established method for
scientific experimentation in chemistry and biology. Examples are
heterogeneous catalysts, drug developments and nanoparticle toxicology.
These methods involve the synthesis of small sample volumes often in
form of particles that are quickly tested. The tests are designed to
quickly obtain easily accessible data (called descriptors) that are
related with a predictor function to the desired properties. One
particle based high-throughput concept for the evaluation of potential
toxicological hazards will be introduced. Furthermore, a new concept is
presented which transfers high-throughput screening to the exploration
of structural metals. The method comprises the synthesis of alloy
samples in form of particles. The samples obtain a defined
microstructure by fast or parallel thermal and mechanical treatments and
are subsequently subjected to fast descriptor tests while a
mathematical algorithm develops the predictor function.